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tecovirimat will increase the level or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep track of. Tecovirimat is often a weak inhibitor of CYP2C8 and CYP2C19. Watch for adverse outcomes if coadministered with sensitive substrates of these enzymes.iloperidone will increase levels of diazepam by influencing hepatic/